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Assuch, there is no cross resistance with any otherclass of AMAs.
On histologic examination, acne is character-ized by retention of the sebum in the isthmus of the hairfollicle, with variable lymphocytic infiltration.
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Thematrix consistsofavarietyofsolutes,includinginorganicions (Na+, K+,Ca2+) and organicmoleculessuch as intermediate metabolites, carbohydrates, lipids, proteins,and RNAs.
The portion ofthe cortex between the medulla andsuperficial cortex isfreeofnodules; it iscalled the deep cortex(paracortex).